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Multi institutional phase II study of concomitant stereotactic reirradiation and cetuximab for recurrent head and neck cancer

✍ Scribed by Lartigau, Eric F.; Tresch, Emmanuelle; Thariat, Juliette; Graff, Pierre; Coche-Dequeant, Bernard; Benezery, Karen; Schiappacasse, Luis; Degardin, Marian; Bondiau, Pierre-Yves; Peiffert, Didier; Lefebvre, Jean-Louis; Lacornerie, Thomas; Kramar, Andrew


Book ID
122328659
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
426 KB
Volume
109
Category
Article
ISSN
0167-8140

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## Abstract ## Background. The management of recurrent unresectable head and neck cancer remains a challenging problem. Based on the circadian rhythm concept, we sought to determine the maximum tolerated dose (MTD) of infusional 5‐flourouracil (5‐FU), hydroxyurea (HU), and reirradiation (RT). ##