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Multi-center phase II trial of chemo-radiotherapy with 5-fluorouracil, leucovorin and oxaliplatin in locally advanced esophageal cancer

✍ Scribed by Vanna Chiarion-Sileni; Roberto Innocente; Raffaele Cavina; Alberto Ruol; Luigi Corti; Jacopo Pigozzo; Paola Del Bianco; Uberto Fumagalli; Armando Santoro; Ermanno Ancona


Publisher
Springer
Year
2008
Tongue
English
Weight
396 KB
Volume
63
Category
Article
ISSN
0344-5704

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Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer