Three days hypoxia (0.5 atm) increased the haemoglobin and haematocrit values in rats paralleled by enhanced intestinal iron absorption. The destination of recently-absorbed iron was primarily the erythropoietic system, viz. bone marrow, spleen and red cells. Total plasma transferrin, was increased
Mucosal transferrin and ferritin factors in the regulation of iron absorption
β Scribed by Fawzi A. El-Shobaki; Walter Rummel
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 728 KB
- Volume
- 171
- Category
- Article
- ISSN
- 0372-8722
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This work was supported by grants from the Progetto Nazionale "Cirrosi epatiea ed epatiti virali" (Unit of Modenar of the Minister0 dell'Universita' e della Ricerca Scientifica e Tecnologica and from CNR. It was presented in part
Isolated non blood-perfused intestinal segments from normal and iron-deficient rats were used in vitro. A modification of the luminal perfusion method according to Fisher and Parsons allowed the comparison of iron and transferrin quantities in the serosal fluid at 15 min intervals. Iron transfer in
Placental transferrin receptors, located at the apical side of syncytiotrophoblast, mediate placental iron uptake. Regulation of transferrin receptors on the fetal-maternal exchange area could be a major determinant in the regulation of trans-placental iron transport. Transferrin receptor expression