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Mucosal metabolism in ulcerative colitis and crohn's disease

โœ Scribed by Maeve M. Duffy; Mark C. Regan; P. Ravichandran; Conor O'Keane; Michael G. Harrington; John M. Fitzpatrick; P. Ronan O'Connell


Publisher
Springer
Year
1998
Tongue
English
Weight
837 KB
Volume
41
Category
Article
ISSN
0012-3706

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Background: Paraoxonase 1 (PON1) is an extracellular enzyme, which in the gastrointestinal tract may act as a local detoxifier, antioxidant, immunomodulator, and/or quorum-quenching factor. There are no data on PON1 activity in Crohn's disease (CD). Methods: PON1 phenotype and activity were determi