Patterns of neoplasia in Crohn's disease and ulcerative colitis
β Scribed by Adrian J. Greenstein; David B. Sachar; Harry Smith; Henry D. Janowitz; Arthur H. Aufses Jr.
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 356 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0008-543X
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The mechanisms of tissue damage in ulcerative colitis and Crohn's disease may reΒ―ect disordered humoral or cell-mediated effector mechanisms, respectively. Mucosal biopsies from untreated inΒ―ammatory bowel disease patients and normal controls were analysed for the expression of granzyme B, a cytotox
Ulcerative colitis (UC) and, to a lesser extent, Crohn's disease (CD) are associated with a reduction of the protective mucus layer in the large intestine; the role of this alteration in the pathogenesis of either disease is, however, not clear. To learn more about the molecular mechanism of the alt