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mTOR kinase, a key player in the regulation of glial functions: Relevance for the therapy of multiple sclerosis

✍ Scribed by Dello Russo, Cinzia; Lisi, Lucia; Feinstein, Douglas L.; Navarra, Pierluigi

Book ID
118758983
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
440 KB
Volume
61
Category
Article
ISSN
0894-1491

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## Abstract ## BACKGROUND. The mammalian target of rapamycin (mTOR) pathway is up‐regulated in many human cancers, and agents targeting the mTOR pathway are in various stages of clinical development. The goal of the study was to evaluate the potential and limitations of targeting the mTOR pathway