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Immune surveillance of the central nervous system in multiple sclerosis — Relevance for therapy and experimental models

✍ Scribed by Hussain, Rehana Z.; Hayardeny, Liat; Cravens, Petra C.; Yarovinsky, Felix; Eagar, Todd N.; Arellano, Benjamine; Deason, Krystin; Castro-Rojas, Cyd; Stüve, Olaf

Book ID: 127093023
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 311 KB
Volume: 276
Category: Article
ISSN: 0165-5728
DOI: 10.1016/j.jneuroim.2014.08.622

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## Abstract Multiple sclerosis is a chronic demyelinating inflammatory disease of the central nervous system (CNS). As the tissue macrophage of the CNS, microglia have the potential to regulate and be regulated by cells of the CNS and by CNS‐infiltrating immune cells. The exquisite sensitivity of m