MS516 UNUSUAL STEROLIC MIXTURE, AND 24-ISOPROPYLCHOLESTEROL, FROM THE SPONGE Ciocalypta sp. REDUCE CHOLESTEROL UPTAKE AND BASOLATERAL SECRETION IN Caco2 CELLS

Unusual sterolic mixture, and 24-isoprop

Unusual sterolic mixture, and 24-isopropylcholesterol, from the sponge Ciocalypta sp. reduce cholesterol uptake and basolateral secretion in Caco-2 cells

✍ Hong Quang Do; Laurianne Van Landeghem; Gaëtane Wielgosz-Collin; Martin Takoudju 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

## Abstract An unusual sterolic mixture (82.3% of 24‐isopropylated sterols) and its major component, 24‐isopropylcholesterol, isolated from a marine sponge, __Ciocalypta__ sp. (Halichondriidae), reduce cholesterol uptake, basolateral secretion and ACAT‐2 mRNA expression and increase the expression