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MRP Subfamily Transporters and Resistance to Anticancer Agents

✍ Scribed by Gary D. Kruh; Hao Zeng; Philip A. Rea; Guosheng Liu; Zhe-Sheng Chen; Kun Lee; Martin G. Belinsky


Book ID
110316920
Publisher
Springer US
Year
2001
Tongue
English
Weight
69 KB
Volume
33
Category
Article
ISSN
0145-479X

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## Abstract Multidrug resistance protein 1 (MRP1) belongs to the ATP‐binding cassette (ABC) transporter family. It is able to transport a broad range of anticancer drugs through cellular membranes, thus limiting their antiproliferative action. Since its discovery in 1992, MRP1 has been the most stu