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MR-guided radiofrequency ablation of hepatic malignancies at 1.5 T: Initial results

✍ Scribed by Andreas H. Mahnken; Arno Buecker; Elmar Spuentrup; Gabriele A Krombach; Dietrich Henzler; Rolf W. Günther; Josef Tacke

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
226 KB
Volume
19
Category
Article
ISSN
1053-1807

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✦ Synopsis

Purpose: To assess the feasibility of magnetic resonance (MR)-guided radiofrequency ablation (RFA) of hepatic malignancies using a high-field MR scanner.

Materials and Methods:

A total of 10 patients with 14 primary (N ϭ 1) or secondary (N ϭ 13) hepatic malignancies underwent MR-guided RFA using a closed-bore 1.5 T MR scanner. Lesion diameters ranged from 2.0 cm to 4.7 cm. RFA was performed using a 200-W generator in combination with a 3.5-cm LeVeen electrode applying a standardized energy protocol.

Results: RFA was technically feasible in all patients. Necrosis diameter ranged from 2.5 cm to 6.8 cm. The mean follow-up period is 12.2 (1-18) months. In nine out of 10 patients, local tumor control was achieved. For this purpose, a second CT-guided RFA was required in two patients. In four patients, multifocal hepatic tumor progression occurred, with the treated lesion remaining tumor-free in three of these patients. Two patients showed extrahepatic tumor progression. Four patients remained tumorfree. No major complications occurred.

Conclusion:

MR-guided RFA of hepatic malignancies in a closed-bore high-field MR scanner is technically feasible and safe. It can be advantageous in locations considered unfavorable for CT-guided puncture or in patients in which iodinated contrast material is contraindicated.

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