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MP-15.10: Effect of Endothelin-1 on Cyclooxygenase-2 Expression in Human Hormone Refractory Prostate Cancer Cells

✍ Scribed by R. Jia; Q. Su; L. Xu; Z. Wang; W. Li; S. Wang

Book ID: 116951798
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 127 KB
Volume: 74
Category: Article
ISSN: 0090-4295
DOI: 10.1016/j.urology.2009.07.844

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## Abstract ## Background. The protooncogenes Ets‐1 and Ets‐2 are involved in carcinogenesis of different tumors. Nimesulide, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has antiproliferative effects on tumor cells. The question arises whether nimesulide influences Ets‐1 and Ets‐2 synthesis in