Mouse skin tumor initiating activity of fluorinated derivatives of 1,2,3,4-tetrahydro-7,12-dimethylbenz[a]anthracene
✍ Scribed by Nair, Raghunathan V.; Walker, Susan E.; Sharma, Pradeep K.; Witiak, Donald T.; DiGiovanni, John
- Book ID
- 126493678
- Publisher
- American Chemical Society
- Year
- 1992
- Tongue
- English
- Weight
- 501 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0893-228X
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## Abstract Syntheses of (8α,9α,10α,11β)‐__trans__‐1,2,3,4,8,9,10,11‐octahydro‐7,12‐dimethyl‐8,9‐epoxybenz[a]anthracene‐10,11‐diol (3) and (8α,9α,10β,11α)‐__trans__‐1,2,3,4,8,9,10,11‐octahydro‐7,12‐dimethyl‐8,9‐epoxybenz[a]anthracene‐10,11‐diol (4), the putative D‐ring metabolites of 1,2,3,4‐tetrah
## Abstract The __cis__‐2a,3‐diol and the __trans__‐4,5‐, __trans__‐7,8‐, __trans__‐9,10‐ and __trans__‐11,12‐dihydrodiols of 3‐methylcholanthrene and the __trans__‐3,4, __trans__‐5,6‐, __trans__‐8,9‐ and __trans__‐10,11‐ dihydrodiols of 7,12‐dimethylbenz[__a__]‐anthrancene have been tested, in com