Mouse monoclonal antibodies in biological research: strategies for high-throughput production
โ Scribed by Pieranna Chiarella; Vito Michele Fazio
- Book ID
- 106364214
- Publisher
- Springer Netherlands
- Year
- 2008
- Tongue
- English
- Weight
- 199 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0141-5492
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๐ SIMILAR VOLUMES
A simple high density cell culture system is described which demonstrates many of the features of commercially available hollow-fibre systems, but without the need to invest in a dedicated system. The system has been shown to achieve product concentrations of up to 40-fold greater than that obtained
As the market for biopharmaceuticals especially monoclonal antibodies (MAbs) rapidly grows, their manufacturing methods are coming under increasing regulatory scrutiny, particularly due to concerns about the potential introduction of adventitious agents from animalsourced components in the media use