𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mouse Models of Myelin Diseases

✍ Scribed by H. Werner; M. Jung; M. Klugmann; M. Sereda; I.R. Griffiths; K.-A. Nave

Book ID
111403907
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
334 KB
Volume
8
Category
Article
ISSN
1015-6305

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

PLP overexpression perturbs myelin prote
PLP overexpression perturbs myelin protein composition and myelination in a mouse model of Pelizaeus-Merzbacher disease
✍ Saadia A. Karim; Jennifer A. Barrie; Mailis C. McCulloch; Paul Montague; Julia M 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 917 KB

## Abstract Duplication of __PLP1__, an X‐linked gene encoding the major myelin membrane protein of the human CNS, is the most frequent cause of Pelizaeus‐Merzbacher disease (PMD). Transgenic mice with extra copies of the wild type __Plp1__ gene, a valid model of PMD, also develop a dysmyelinating

Mouse models of human diseases
Mouse models of human diseases
✍ Heiner Westphal 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 391 KB

Cancer, poliomyelitis, Alzheimer's and Gaucher disease, a seemingly disparate array of disorders, have become the target of powerful genetic analysis and drug screening protocols, using mouse strains that have been genetically altered to serve as models for understanding the disease and for helping