𝔖 Bobbio Scriptorium
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Mouse models of Huntington's disease

✍ Scribed by Liliana B Menalled; Marie-Françoise Chesselet


Book ID
117340724
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
103 KB
Volume
23
Category
Article
ISSN
0165-6147

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Increased GABAergic function in mouse mo
✍ Carlos Cepeda; Amaal J. Starling; Nanping Wu; Oanh K. Nguyen; Besim Uzgil; Takah 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 559 KB

## Abstract Huntington's disease (HD) is characterized by loss of striatal γ‐aminobutyric acid (GABA)ergic medium‐sized spiny projection neurons (MSSNs), whereas some classes of striatal interneurons are relatively spared. Striatal interneurons provide most of the inhibitory synaptic input to MSSNs