✦ LIBER ✦

183. Mouse models of Huntington’s disease

✍ Scribed by C.A. Ross

Book ID: 119407846
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 13 KB
Volume: 47
Category: Article
ISSN: 0006-3223
DOI: 10.1016/s0006-3223(00)00446-7

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## Abstract Huntington disease (HD) is an autosomal dominant disorder in which degeneration of medium‐sized spiny striatal neurons occurs. The HD gene and the protein it encodes, huntingtin, have been identified but their functions remain unknown. Transgenic mouse models for HD have been developed