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Motor neuron disease and frontotemporal dementia: sometimes related, sometimes not

โœ Scribed by Hardy, John; Rogaeva, Ekaterina


Book ID
121420708
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
996 KB
Volume
262
Category
Article
ISSN
0014-4886

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It has been recently demonstrated that the 43-kDa transactive response (TAR)-DNA-binding protein (TARDBP) is the neuropathological hallmark of Frontotemporal Dementia (FTD) with ubiquitin-positive and tau-negative inclusions. Large series of FTD patients without motor neuron disease have been previo