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Motor dysfunction in a mouse model for Down syndrome

✍ Scribed by Alberto C.S Costa; Kathryn Walsh; Muriel T Davisson

Book ID
117199333
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
220 KB
Volume
68
Category
Article
ISSN
0031-9384

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Ts65Dn mice are a genetic model for Down syndrome. Both individuals with Down syndrome and Ts65Dn mice have reduced cerebellar volumes and the cerebellum is involved in motor learning. ConΒ―icting results have been reported on the motor learning abilities of Ts65Dn mice, which may be related to proce