Mothers' active and passive smoking during pregnancy and risk of brain tumours in children

✍ Scribed by G. Filippini; M. Farinotfi; G. Lovicu; P. Maisonneuve; P. Boyle

• Publisher: John Wiley and Sons
• Year: 1994
• Tongue: French
• Weight: 699 KB
• Volume: 57
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910570602

✦ Synopsis

As part of a collaborative study of risk factors for childhood brain tumours, the effects of the mother's smoking and her potential for passive smoking exposure during the pregnancy were assessed in a case-control study. Parents of 9 I cases and 32 I population controls from Northern Italy, matched for age, sex and residence, were interviewed about their lifetime smoking habits. Mother's smoking during pregnancy was associated with an odds ratio (OR) of I .7 (95% CI 0.8,3.8) of brain tumour in her child although this was not statistically significant. Among non-smoking mothers, the risk for light and heavy exposure to passive smoking was I .7 (0.8,3.6) and 2.2 (I. I, 4.5) respectively, and a statistically significant dose-response relationship was found (p trend = 0.02). These results must be interpreted 4To whom correspondence and reprint requests should be addressed.