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Morusin from Morus Australis Roots Inhibits 12-O-tetradecanoylphorbol-13-Acetate Induced Transformation of Epidermal JB6 Cells

✍ Scribed by Tseng, Tsui-Hwa; Chung, Wei-Chia; Lee, Wes; Lee, Yean-Jang

Book ID
122898240
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
44 KB
Volume
106
Category
Article
ISSN
0006-3495

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## Abstract Neoplastic transformation and transcriptional activation by activator protein‐1 (AP‐1) complex are stimulated by tumor‐promoting agents in promotion‐sensitive (P^+^) but not promotion‐resistant (P^‐^) mouse epidermal JB6 cells in culture. This implicates AP‐1 as a specific regulator of