๐”– Bobbio Scriptorium
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Morphology of tumors induced in Hamsters by Simian adenoviruses

โœ Scribed by I. S. Levenbook; A. E. Chigirinsky; E. M. Tsetlin; N. N. Dodonova; A. D. Altstein

Publisher
John Wiley and Sons
Year
1968
Tongue
French
Weight
918 KB
Volume
3
Category
Article
ISSN
0020-7136

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โœฆ Synopsis

Subcutaneous hamster tumors induced by Simian adenovirus SA7, strains C8, B105 and C626, were found to be poorly difJerentiated sarcomas having morphological features which distinguish them from tumors induced at the same site by papovaviruses and the Rous sarcoma virus. In general, the adenovirus-induced tumors were morphologically alike, C8-induced sarcomas showing some di'erences. Tumors induced by this strain in the subcutaneous tissue, muscles, peritoneum and mediastinum were morphologically identical. Tumors found in the brain were mainly malignant ependymomas and choroid plexus carcinomas, generally originating in neuroectodeum.

The oncogenicity of adenovirus SA7 ( C 8 ) in meso-and ectodermal cells has thus been demonstrated.

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