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Morphological transformation of cells by cyclopenta-fused derivatives of benzo[a]pyrene and benzo[e]pyrene☆

✍ Scribed by Nesnow, Stephen; Beck, Susan; Ball, Louise M.; Sangaiah, R.; Gold, Avram

Book ID
123017666
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
516 KB
Volume
74
Category
Article
ISSN
0304-3835

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## Abstract The frequency of cell transformation was determined after treatment of normal hamster embryo cells with benzo(a)pyrene (BP) and six of its metabolites. These metabolites included the __trans__ 4,5‐, 7,8‐ and 9,10‐dihydrodiols; the 4,5‐epoxide; and two stereoisomers of the non‐K‐region d