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Morphological changes and molecular expressions of hepatocellular carcinoma cells in three-dimensional culture model

✍ Scribed by Ya-Mei Wu; Juan Tang; Pu Zhao; Zhi-Nan Chen; Jian-Li Jiang

Book ID
113956638
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
520 KB
Volume
87
Category
Article
ISSN
0014-4800

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## Abstract Cisplatin is a clinically important chemotherapeutical agent used to treat epithelial malignancies. High concentrations (20–100 ΞΌM) of cisplatin have been used in numerous studies to induce apoptosis of carcinoma cells grown in monolayer culture over 24–48 hr. These conditions may not b