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Morpholino antisense oligonucleotides: tools for investigating vertebrate development

✍ Scribed by Corey, David R. (author);Abrams, John M. (author)

Book ID
120703009
Publisher
BioMed Central
Year
2001
Tongue
English
Weight
73 KB
Volume
2
Category
Article
ISSN
1465-6906

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## Abstract ## Background Antisense‐mediated exon skipping is a putative treatment for Duchenne muscular dystrophy (DMD). Using antisense oligonucleotides (AONs), the disrupted DMD reading frame is restored, allowing generation of partially functional dystrophin and conversion of a severe Duchenne