Retinoic acid is a good candidate for a morphogen in chick limb bud development. The challenge now is to determine how retinoic acid interacts with limb bud cells and how the retinoic acid signal is integrated with other signals to mould and pattern the developing limb.
โฆ LIBER โฆ
Morphogen gradients in vertebrate limb development
โ Scribed by Cheryll Tickle
- Book ID
- 115647450
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 194 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1084-9521
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## Abstract The idea that concentration gradients of crucial substances might control the pattern of development, even in the embryos of complex organisms, has been around for a long time, but mostly in obscure forms. Twenty five years ago clear, experimentally testable ideas about how such gradien