๐”– Bobbio Scriptorium
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Morphine tolerance and dependence in the locus coeruleus: Single cell studies in brain slices

โœ Scribed by Rodrigo Andrade; Cam P. Vandermaelen; George K. Aghajanian


Book ID
115878017
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
680 KB
Volume
91
Category
Article
ISSN
0014-2999

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Ng-nitro-L-arginine (L-NArg), a potent nitric oxide synthase inhibitor, has been implicated as a potential mechanism for attenuating the development of tolerance to opioid drugs and for suppressing opioid withdrawal. Neurons in the locus coeruleus (LC) express opioid receptors and these neurons exhi