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Common α2- and opiate effector mechanisms in the locus coeruleus: intracellular studies in brain slices

✍ Scribed by G.K. Aghajanian; Y.-Y. Wang

Book ID
118955659
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
861 KB
Volume
26
Category
Article
ISSN
0028-3908

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The firing rate of locus coeruleus (LC) neurons in rat brain slices was increased reversibly by agents that either elevate intracellular levels of adenosine 3'3'cyclic monophosphate (CAMP) or mimic its actions (e.g., forskolin, an activator of adenylate cyclase, 8-Br-cAMP, a membrane permeable analo