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Morphine-induced skin wheals: A possible model for the study of histamine release

✍ Scribed by Saucedo, Roberto; Erill, Sergio


Book ID
109843701
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
304 KB
Volume
38
Category
Article
ISSN
0009-9236

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Basophil activation studies commonly rely on the measurement of histamine following extraction and condensation to o-phthalaldehyde (OPT) as a quantitative measurement of degranulation. Specificity has long been recognized as a problem with this method. We have described a new high-performance liqui