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Morphine decreases the voltage sensitivity of slow sodium channels

โœ Scribed by B. V. Krylov; A. V. Derbenev; S. A. Podzorova; M. I. Lyudyno; A. V. Kuz'min; N. L. Izvarina

Book ID
105584881
Publisher
Springer US
Year
2000
Tongue
English
Weight
759 KB
Volume
30
Category
Article
ISSN
0097-0549

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Action potentials in mammalian nerve and muscle are generated by a stereotyped sequence of alterations in membrane conductance to monovalent cations [ 1,2]. The fundamental change that leads to the initiation of an action potential is a regenerative, but self-limited, increase in membrane conductanc