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Montelukast, a Cysteinyl Leukotriene Receptor-1 Antagonist, Dose- and Time-Dependently Protects against Focal Cerebral Ischemia in Mice

✍ Scribed by Yu, Guo-Liang; Wei, Er-Qing; Zhang, Shi-Hong; Xu, Hui-Ming; Chu, Li-Sheng; Zhang, Wei-Ping; Zhang, Qi; Chen, Zhong; Mei, Ru-Huan; Zhao, Meng-Hui

Book ID
119984488
Publisher
S. Karger AG
Year
2004
Tongue
English
Weight
386 KB
Volume
73
Category
Article
ISSN
0031-7012

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Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats
✍ Rui Zhao; Wen-Zhen Shi; Yong-Mei Zhang; San-Hua Fang; Er-Qing Wei πŸ“‚ Article πŸ“… 2011 πŸ› Pharmaceutical Press 🌐 English βš– 579 KB

## Abstract ## Objectives Previously we demonstrated the neuroprotective effect of montelukast, a cysteinyl leukotriene receptor-1 (CysLT1) antagonist, on acute brain injury after focal cerebral ischaemia in mice. In this study, we have determined its effect on chronic brain injury after focal cer