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Pranlukast, a cysteinyl leukotriene receptor-1 antagonist, protects against chronic ischemic brain injury and inhibits the glial scar formation in mice

✍ Scribed by Guo-Liang Yu; Er-Qing Wei; Meng-Ling Wang; Wei-Ping Zhang; Shi-Hong Zhang; Jie-Qun Weng; Li-Sheng Chu; San-Hua Fang; Yu Zhou; Zhong Chen; Qi Zhang; Li-Hui Zhang

Book ID: 113500767
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 549 KB
Volume: 1053
Category: Article
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2005.06.046

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## Abstract ## Objectives Previously we demonstrated the neuroprotective effect of montelukast, a cysteinyl leukotriene receptor-1 (CysLT1) antagonist, on acute brain injury after focal cerebral ischaemia in mice. In this study, we have determined its effect on chronic brain injury after focal cer