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Monovalent Ion-mediated Folding of the Tetrahymena thermophila Ribozyme

✍ Scribed by Inna Shcherbakova; Sayan Gupta; Mark R. Chance; Michael Brenowitz


Book ID
116661545
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
532 KB
Volume
342
Category
Article
ISSN
0022-2836

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## Abstract **Background:** The __Tetrahymena__ group I ribozyme folds into a complex three‐dimensional structure for performing catalytic reactions. The catalysis depends on its catalytic core consisting of two helical domains, P4–P6 and P3–P7, connected by single stranded regions. In the folding