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The kinetic folding pathway of the Tetrahymena ribozyme reveals possible similarities between RNA and protein folding

✍ Scribed by Zarrinkar, Patrick P.; Williamson, James R.


Book ID
109964815
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
673 KB
Volume
3
Category
Article
ISSN
1072-8368

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## Abstract **Background:** The __Tetrahymena__ group I ribozyme folds into a complex three‐dimensional structure for performing catalytic reactions. The catalysis depends on its catalytic core consisting of two helical domains, P4–P6 and P3–P7, connected by single stranded regions. In the folding