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Monovalent Cations Sequester within the A-Tract Minor Groove of [d(CGCGAATTCGCG)] 2†,§

✍ Scribed by Woods, Kristen Kruger; McFail-Isom, Lori; Sines, Chad C.; Howerton, Shelley B.; Stephens, Rasheeda K.; Williams, Loren Dean

Book ID
126472123
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
52 KB
Volume
122
Category
Article
ISSN
0002-7863

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The structures of the complexes formed between two anticancer minor-groove-binding quinolinium quaternary salts and the dodecamer d(CGCGAATTCGCG) 2 have been refined to resolutions of 1.6 and 1.8 A ˚. The complexes crystallized in space group P2 1 2 1 2 1 and the structures are isomorphous with prev