A polymalformed newborn with partial monosomy for the long arm of chromosome 16 is presented. Karyotype 46,XX,del(16)(q21). Numerical abnormalities of chromosome 16 have never been reported in liveborn infants, and only one case of partial trisomy for the long arm of chromosome 16 in a polymalforme
Monosomy 21: A possible stepwise evolution of the karyotype
โ Scribed by Abeliovich, Dvorah ;Carmi, Rivka ;Karplus, Michael ;Bar-Ziv, Jacob ;Cohen, Maimon M. ;Summitt, R. L.
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 458 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0148-7299
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Reexamination was made on a male infant previously reported as 21-monosomy. Extensive chromosome banding analyses in the patient and parents disclosed an unbalanced de novo translocation between chromosomes 13 and 21. The patient's karyotype was interpreted as 45,XY,--13,--21+der(13),t(13;21) (q2 or
## Abstract The sister chromatid exchange (SCE) frequencies of six freshly established and two old cell lines derived from patients with lymphatic tumors or leukemia were compared to the SCE rates of lymphoblastoid cell lines of normal controls. All cell lines from malignant tumors displayed signif