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Monooxygenase-Mediated Baeyer−Villiger Oxidations

✍ Scribed by Marko D. Mihovilovic; Bernhard Müller; Peter Stanetty


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
332 KB
Volume
2002
Category
Article
ISSN
1434-193X

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Combinations of axially chiral C2-symmetric diols were used as ligands in zirconium-mediated Baeyer-Villiger reactions. The in situ preformed Zr-diol species proved effective in the asymmetric oxidation of bicyclic and monosubstituted cyclobutanones when a hydroperoxide was employed as oxidant. Asym