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Baeyer—Villiger Oxidations

✍ Scribed by Sabine Flitsch; Gideon Grogan


Publisher
John Wiley and Sons
Year
2003
Weight
48 KB
Volume
34
Category
Article
ISSN
0931-7597

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Combinations of axially chiral C2-symmetric diols were used as ligands in zirconium-mediated Baeyer-Villiger reactions. The in situ preformed Zr-diol species proved effective in the asymmetric oxidation of bicyclic and monosubstituted cyclobutanones when a hydroperoxide was employed as oxidant. Asym