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Mononucleotide markers of microsatellite instability in carcinomas of the urinary bladder

✍ Scribed by A.A Saetta; A Goudopoulou; P Korkolopoulou; G Voutsinas; E Thomas-Tsagli; N.V Michalopoulos; E Patsouris

Book ID
116442259
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
420 KB
Volume
30
Category
Article
ISSN
0748-7983

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Tumors lacking DNA mismatch repair activity (MMR) from patients with Hereditary Nonpolyposis Colorectal Cancer (HNPCC) or those with sporadic colorectal cancer can be identified by the presence of high levels of instability in repetitive sequences known as microsatellites (MSI). The assessment of MS