Monoclonal antibody αIR-3 inhibits non-s
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Farah Zia; Steve Jacobs; Frederick Kull Jr.; Frank Cuttitta; James L. Mulshine;
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Article
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1996
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John Wiley and Sons
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English
⚖ 601 KB
The ability of monoclonal antibody (mAb) alR-3 to interact with non-small cell lung cancer (NSCLC) cells was investigated. MAb alR-3 inhibited specific binding of 1251-IGF-I and 1251-alR-3 to a panel of 8 NSCLC cell lines with high affinity (IC50 = 200 and 50 ng/ml, respectively). 1251-alR-3 bound w