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Monoclonal antibody to human trk-A: diagnostic and therapeutic potential in neuroblastoma

✍ Scribed by K Kramer; W Gerald; L LeSauteur; H.U Saragovi; N.-K.V Cheung

Book ID
117663936
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
43 KB
Volume
33
Category
Article
ISSN
0959-8049

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## Abstract Monoclonal antibody UJ13A radiolabelled with isotopes of iodine has been shown to selectively localize to human neuroblastoma xenografts. When ^131^I‐UJ13A conjugates were given to nude mice at high doses (100–150 ΞΌCi), tumours temporarily disappeared, only to regrow. No selection for n