๐”– Bobbio Scriptorium
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Monoclonal antibody therapy for the induction of transplantation tolerance

โœ Scribed by Stephen P. Cobbold

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
422 KB
Volume
29
Category
Article
ISSN
0165-2478

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The therapeutic effectiveness of xenogeneic monoclonal antibodies (MAbs) (xIg) or their conjugates with toxins (xIg-Tx) is undermined because of their inherent immunogenicity. This complication may be overcome by converting the antigenic xIg to tolerogenic derivatives by coupling an appropriate numb