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Monoclonal antibody C3.1 is a platelet derived growth factor (PDGF) antagonist

✍ Scribed by Rodney S. Kawahara; Barbara B. Kennedy; Thomas F. Deuel

Book ID: 115760610
Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 923 KB
Volume: 147
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(87)91006-0

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## Abstract Platelet‐derived growth factors (PDGFs) are paracrine growth factors mediating epithelial–mesenchymal interactions and exerting multiple biological activities which include cell proliferation, motility, and differentiation. As previously demonstrated, PDGFs act during embryonic developm