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Monoclonal Antibody against Epidermal Growth Factor Receptor is Internalized without Stimulating Receptor Phosphorylation

✍ Scribed by Hironobu Sunada, Bruce E. Magun, John Mendelsohn and Carol L. MacLeod

Book ID
123633049
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
909 KB
Volume
83
Category
Article
ISSN
0027-8424

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A monoclonal antibody to the human epide
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✍ Michael D. Waterfield; Elaine L. V. Mayes; Paul Stroobant; Paul L. P. Bennet; Su πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 844 KB

## Abstract A monoclonal antibody of the IgG class, EGFR1, has been isolated using cells of the epidermoid carcinoma line A431 as immunogen. The A431 antigen recognized by EGFR1 has an apparent molecular weight of approximately 175,000, is a cell‐surface molecule which can be specifically cross‐lin