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Monoclonal antibodies to p24-core protein of HIV-1 mediate ADCC and inhibit virus spread in vitro

✍ Scribed by Grunow, Roland; Franke, Lutz; Hinkula, Jorma; Wahren, Britta; Fenyö, Eva-Maria; Jondal, Mikael; von Baehr, Rüdiger


Book ID
122614813
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
631 KB
Volume
3
Category
Article
ISSN
0928-0197

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## Abstract Murine monoclonal antibodies (Mabs) to the major core protein p24 of the human immunodeficiency virus type 1 (HIV‐1) were tested for their ability to inhibit the replication and spread __of__ the virus in permanent cell cultures (Molt4/8, K37, H9) and in the culture of 11‐2 stimulated T