Monoclonal antibodies were raised against hepatitis B core antigen (HBcAg) synthesized in Escherichia coli. They identified a single immunodominant determinant on both liver-derived and E. coli-derived HBcAg. Cross-inhibition studies demonstrated that HBsAg-containing human sera which contained anti
Monoclonal antibodies against an immunodominant and neutralizing epitope on hepatitis A virus antigen
β Scribed by D. Crevat; J. M. Crance; A. M. Chevrinais; J. Passagot; E. Biziagos; G. Somme; R. Deloince
- Publisher
- Springer Vienna
- Year
- 1990
- Tongue
- English
- Weight
- 338 KB
- Volume
- 113
- Category
- Article
- ISSN
- 1432-8798
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In vitro HBV infection and neutralization were assayed using an anti-preS1 murine monoclonal antibody (1B3) and anti-preS2 (H69K) and anti-S (CS131A) murine-human chimeric antibodies. The 1B3 (IgG1) and H69K (IgG1) was constructed previously and the CS131A was constructed for this study by expressin
A recombinant subunit antigen (ORF2.1), representing the carboxy-terminal 267 amino acids of the 660-amino-acid hepatitis E virus (HEV) capsid protein, was expressed in Escherichia coli and used for the immunisation of rats. Purified antigen formulated with either Aluminium Hydroxide Gel Adjuvant (A
## Abstract The hepatitis C virus (HCV) nonstructural 3 (NS3) protein is composed of an amino terminal protease and a carboxyl terminal RNA helicase. NS3 contains major antigenic epitopes. The antibody response to NS3 appears early in the course of infection and is focused on the helicase region. H