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Mono-allelic Expression of Variegating Transgene Locus in the Mouse

✍ Scribed by Margaret L. Opsahl; Anthea Springbett; Richard Lathe; Alan Colman; Margaret McClenaghan; C. Bruce A. Whitelaw

Book ID
111613817
Publisher
Springer Netherlands
Year
2003
Tongue
English
Weight
243 KB
Volume
12
Category
Article
ISSN
0962-8819

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✍ Estela GimΓ©nez; Patricia Giraldo; Glen Jeffery; LluΓ­s Montoliu πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 407 KB

## Abstract Summary: Deletion of the tyrosinase locus control region (LCR) in transgenic mice results in variegated expression in the skin. Here we investigate the pigmentation pattern of other tissues that express tyrosinase: iris, choroid, and retina in the same animals. A mosaic distribution of