𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Monitoring the solid phase synthesis of analogues of lysobactin and the katanosins using in situ MALDI-TOF MS

✍ Scribed by Bryan J. Egner; Mark Bradley

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
624 KB
Volume
53
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

✦ Synopsis

A method of solid phase reaction analysis is described using an in situ cleavage process (TFA vapour) followed by MALDI-TOF MS analysis. The process is demonstrated by the solid phase synthesis of a depsipeptide based on the antibiotic Lysobactin.

📜 SIMILAR VOLUMES

Anionic Polymerization of Ethylene Oxide
Anionic Polymerization of Ethylene Oxide in the Presence of the Phosphazene Base ButP4 – Kinetic Investigations Using In-Situ FT-NIR Spectroscopy and MALDI-ToF MS
✍ Holger Schmalz; Michael G. Lanzendörfer; Volker Abetz; Axel H. E. Müller 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 275 KB

## Abstract Fourier‐transform near‐infrared (FT‐NIR) fiber‐optic spectroscopy was successfully used to monitor the anionic polymerization of ethylene oxide (EO). Kinetic data are provided for the polymerization of EO with the __sec__‐BuLi/Bu^__t__^P~4~ initiating system under different reaction con

Application of time-of-flight secondary
Application of time-of-flight secondary ion mass spectrometry toin situ monitoring of solid-phase peptide synthesis on the MultipinTM system
✍ Aubagnac, J.-L.; Enjalbal, C.; Subra, G.; Bray, A. M.; Combarieu, R.; Martinez, 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB 👁 2 views

In the rapidly growing Ðeld of combinatorial chemistry, the Multipin approach has been used for rapid and efficient multiple parallel syntheses of organic compounds. This strategy is particularly well adapted for the optimization of reaction conditions prior to chemical library syntheses, for the pr

Monitoring of the principal carbonyl com
Monitoring of the principal carbonyl compounds involved in malolactic fermentation of wine by solid-phase microextraction and positive ion chemical ionization GC/MS analysis
✍ Riccardo Flamini; Antonio Dalla Vedova; Annarita Panighel; Nicola Perchiazzi; St 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB

## Abstract A new method has been developed to determine acetaldehyde, 2,3‐butanedione (diacetyl) and 3‐hydroxy‐2‐butanone (acetoin) in wine by solid‐phase microextraction (SPME) and positive ion chemical ionization GC/MS analysis of __O__‐(2,3,4,5,6‐pentafluorobenzyl)‐hydroxylamine (PFBOA) derivat