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Monitoring the fidelity of mitotic chromosome segregation by the spindle assembly checkpoint

✍ Scribed by P. Silva; J. Barbosa; A. V. Nascimento; J. Faria; R. Reis; H. Bousbaa


Book ID
108678047
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
682 KB
Volume
44
Category
Article
ISSN
0960-7722

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## Abstract Mitotic catastrophe is a form of cell death that results from aberrant mitosis. Currently, the mechanisms involved in this form of cell death remain poorly understood. We found that actinomycin D induces mitotic catastrophe with severe spindle assembly defects. We have studied the natur