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Monitoring in clinical trials: benefit or bias?

✍ Scribed by Cecilia Nardini


Book ID
120749838
Publisher
Springer Netherlands
Year
2013
Tongue
English
Weight
189 KB
Volume
34
Category
Article
ISSN
1573-1200

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Patient non-compliance and drop-out can bias analyses of clinical trial data. I describe a parametric model for treatment cross-over and drop-out and demonstrate how the concept of ignorability, originally de"ned for incomplete-data problems, can elucidate sources of bias in clinical trials. I discu