Monitoring CMV-Specific CD8+ T-Cell Responses After Allogeneic Stem Cell Transplantation: A New Way of Guiding Anti-Viral Therapy
✍ Scribed by Zabalza, Amaya; Ciaurriz, Miriam; Beloki, Lorea; Ramirez, Natalia; Gorosquieta, Ana; Calvillo, Mercedes Rodriguez; Bandres, Eva; Mansilla, Cristina; Olavarria, Eduardo
- Book ID
- 123404518
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 54 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1083-8791
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## Abstract We studied the recovery of CMV‐specific CD4^+^ and CD8^+^ T‐cell immunity in 52 recipients of allogeneic stem cell transplantation (SCT). The proportions of IFN‐γ‐producing CD4^+^ and CD8^+^ T cells upon in vitro activation using peptide pools representing the CMV pp65 and IE‐1 proteins
## Abstract Reconstitution of human cytomegalovirus (HCMV) T‐cell immunity is crucial in hematopoietic stem cell transplant (HSCT) recipients. The QuantiFERON®‐CMV assay for cellular HCMV‐specific immunity was evaluated in allogeneic HSCT recipients (n = 43) and patients with hematological malignan
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